商品介绍

gene_symbol：Adenylate Kinase 1
Synonyms：HTL-S-58j
clone_name：OTI19D1
immunogen：Full length human recombinant protein of human AK1 (NP_000467) produced in HEK293T cell.
predicted_size：21.6 kDa
background：Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG2b
host：Mouse
applications：FC, IF, WB
Recommend Dilution：WB 1:1000~2000, IF 1:50, FLOW 1:100
reactivities：Human, Monkey, Mouse, Rat
storage：Store at -20°C as received.