商品介绍

gene_symbol：Prothrombin
Synonyms：PT; RPRGL2; THPH1
clone_name：OTI5G10
immunogen：Human recombinant protein fragment corresponding to amino acids 44-622 of human F2 (NP_000497) produced in HEK293T cell.
predicted_size：70.01 kDa
background：Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG2a
host：Mouse
applications：WB
Recommend Dilution：WB 1:500
reactivities：Human
storage：Store at -20°C as received.