商品介绍

gene_symbol：IL6R
Synonyms：CD126; gp80; IL-6R-1; IL-6RA; IL6Q; IL6RA; IL6RQ
clone_name：OTI2F4
immunogen：Full length human recombinant protein of human IL6R(NP_000556) produced in HEK293T cell.
predicted_size：49.8 kDa
background：This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, May 2011]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG1
host：Mouse
applications：IF, IHC, WB
Recommend Dilution：WB 1:4000, IHC 1:150, IF 1:100
reactivities：Human
storage：Store at -20°C as received.