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gene_symbol:IL2
Synonyms:IL-2; lymphokine; TCGF
clone_name:OTI5A9
immunogen:Human recombinant protein fragment corresponding to amino acids 21-153 of human IL2 (NP_000577) produced in E.coli.
predicted_size:17.4 kDa
background:The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2a
host:Mouse
applications:IHC, WB
Recommend Dilution:IHC 1:500
reactivities:Human
storage:Store at -20°C as received.
gene_symbol:IL2
Synonyms:IL-2; lymphokine; TCGF
clone_name:OTI5A9
immunogen:Human recombinant protein fragment corresponding to amino acids 21-153 of human IL2 (NP_000577) produced in E.coli.
predicted_size:17.4 kDa
background:The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2a
host:Mouse
applications:IHC, WB
Recommend Dilution:IHC 1:500
reactivities:Human
storage:Store at -20°C as received.