商品介绍

gene_symbol：TNF alpha
Synonyms：DIF; TNF-alpha; TNFA; TNFSF2
clone_name：OTI1H3
immunogen：Full length human recombinant protein of human TNF(NP_000585) produced in HEK293T cell.
predicted_size：25.5 kDa
background：This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG2a
host：Mouse
applications：FC, WB
Recommend Dilution：WB 1:4000
reactivities：Human
storage：Store at -20°C as received.