商品介绍

gene_symbol：CD4
Synonyms：CD4mut; IMD79; OKT4D
clone_name：OTI7F2
immunogen：Full length human recombinant protein of human CD4 (NP_000607) produced in HEK293T cell.
predicted_size：48.3 kDa
background：This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG2a
host：Mouse
applications：IHC, WB
Recommend Dilution：WB 1:2000, IHC 1:150
reactivities：Human
storage：Store at -20°C as received.