商品介绍

gene_symbol：TGF beta 1
Synonyms：CED; DPD1; LAP; TGFB; TGFbeta
clone_name：OTI1E12
immunogen：Full length human recombinant protein of human TGFB1(NP_000651) produced in HEK293T cell.
predicted_size：44 kDa
background：This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Oct
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG2a
host：Mouse
applications：FC, IF, WB
Recommend Dilution：WB 1:1000, IF 1:100, FLOW 1:50
reactivities：Human, Mouse, Rat
storage：Store at -20°C as received.