商品介绍

gene_symbol：Angiotensin Converting Enzyme 1
Synonyms：ACE1; CD143; DCP; DCP1
clone_name：OTI2C8
immunogen：Human recombinant protein fragment corresponding to amino acids 642-1230 of human ACE (NP_000780) produced in E.coli.
predicted_size：
background：This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG1
host：Mouse
applications：IHC, WB
Recommend Dilution：WB 1:500~2000, IHC 1:500
reactivities：Human
storage：Store at -20°C as received.