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gene_symbol:DHFR
Synonyms:DHFRP1; DYR
clone_name:OTI3A11
immunogen:Full-length protein expressed in 293T cell transfected with human DHFR expression vector
predicted_size:21.5 kDa
background:Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2b
host:Mouse
applications:IHC, WB
Recommend Dilution:WB: 1:200 - 1:1000 IHC 1:50
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.
gene_symbol:DHFR
Synonyms:DHFRP1; DYR
clone_name:OTI3A11
immunogen:Full-length protein expressed in 293T cell transfected with human DHFR expression vector
predicted_size:21.5 kDa
background:Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2b
host:Mouse
applications:IHC, WB
Recommend Dilution:WB: 1:200 - 1:1000 IHC 1:50
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.