商品介绍

gene_symbol：FOLR2
Synonyms：BETA-HFR; FBP; FR-BETA; FR-P3; PL-1
clone_name：OTI5B1
immunogen：Human recombinant protein fragment corresponding to amino acids 20-221 of human FOLR2(NP_000794) produced in E.coli.
predicted_size：29.1 kDa
background：The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG2a
host：Mouse
applications：IHC, WB
Recommend Dilution：WB 1:200, IHC 1:150
reactivities：Human
storage：Store at -20°C as received.