商品介绍

gene_symbol：IGF1 Receptor
Synonyms：CD221; IGFIR; IGFR; JTK13
clone_name：OTI11E4
immunogen：Human recombinant protein fragment corresponding to amino acids 741-935 of human IGF1R(NP_000866) produced in Insect.
predicted_size：81 kDa
background：This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG1
host：Mouse
applications：FC, WB
Recommend Dilution：WB 1:500
reactivities：Human, Mouse, Rat
storage：Store at -20°C as received.