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gene_symbol:IL2 Receptor beta
Synonyms:CD122; IL15RB; P70-75
clone_name:OTI5A5
immunogen:Human recombinant protein fragment corresponding to amino acids 27-240+Mouse FC of human IL2RB (NP_000869) produced in HEK293T cell.
predicted_size:61.12 kDa
background:The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:WB
Recommend Dilution:WB 1:500
reactivities:Human
storage:Store at -20°C as received.
gene_symbol:IL2 Receptor beta
Synonyms:CD122; IL15RB; P70-75
clone_name:OTI5A5
immunogen:Human recombinant protein fragment corresponding to amino acids 27-240+Mouse FC of human IL2RB (NP_000869) produced in HEK293T cell.
predicted_size:61.12 kDa
background:The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:WB
Recommend Dilution:WB 1:500
reactivities:Human
storage:Store at -20°C as received.