商品介绍

gene_symbol：IMPDH2
Synonyms：IMPD2; IMPDH-II
clone_name：OTI2F10
immunogen：Full length human recombinant protein of human IMPDH2 (NP_000875) produced in HEK293T cell.
predicted_size：55.6 kDa
background：This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG1
host：Mouse
applications：WB
Recommend Dilution：WB 1:2000
reactivities：Human, Mouse, Rat
storage：Store at -20°C as received.