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gene_symbol:AP2M1
Synonyms:AP50; CLAPM1; mu2
clone_name:OTI1F10
immunogen:Human recombinant protein fragment corresponding to amino acids 97-383 of human AP2M1 (NP_001020376) produced in E.coli.
predicted_size:49.2 kDa
background:This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2a
host:Mouse
applications:FC, IF, WB
Recommend Dilution:WB 1:2000, IF 1:100, FLOW 1:100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.
gene_symbol:AP2M1
Synonyms:AP50; CLAPM1; mu2
clone_name:OTI1F10
immunogen:Human recombinant protein fragment corresponding to amino acids 97-383 of human AP2M1 (NP_001020376) produced in E.coli.
predicted_size:49.2 kDa
background:This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2a
host:Mouse
applications:FC, IF, WB
Recommend Dilution:WB 1:2000, IF 1:100, FLOW 1:100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.