商品介绍

gene_symbol：PKR
Synonyms：EIF2AK1; LEUDEN; PKR; PPP1R83; PRKR
clone_name：OTI3F5
immunogen：Human recombinant protein fragment corresponding to amino acids 51-191 of human EIF2AK2 (NP_001129123) produced in E.coli.
predicted_size：61.9 kDa
background：The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG1
host：Mouse
applications：IHC, WB
Recommend Dilution：WB 1:500, IHC 1:500
reactivities：Human
storage：Store at -20°C as received.