商品介绍

gene_symbol：FH
Synonyms：FMRD; HLRCC; LRCC; MCL; MCUL1
clone_name：OTI1F10
immunogen：Full length human recombinant protein of human FH (NP_000134) produced in HEK293T cell.
predicted_size：50.2 kDa
background：The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG1
host：Mouse
applications：FC, IF, IHC, WB
Recommend Dilution：WB 1:1000, IHC 1:50, IF 1:100, FLOW 1:100
reactivities：Human, Dog, Rat, Mouse
storage：Store at -20°C as received.