商品介绍

gene_symbol：CD137
Synonyms：4-1BB; CD137; CDw137; ILA
clone_name：OTI7F9
immunogen：Human recombinant protein fragment corresponding to amino acids 24-186 of human TNFRSF9 (NP_001552) produced in E.coli.
predicted_size：
background：The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG1
host：Mouse
applications：WB
Recommend Dilution：WB 1:2000
reactivities：Human
storage：Store at -20°C as received.