商品介绍

gene_symbol：R Cadherin
Synonyms：CAD4; R-CAD; RCAD
clone_name：OTI4F5
immunogen：Human recombinant protein fragment corresponding to amino acids 170-428 of human CDH4 (NP_001785) produced in E.coli.
predicted_size：98.3 kDa
background：This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG1
host：Mouse
applications：IHC, WB
Recommend Dilution：WB 1:500, IHC 1:150
reactivities：Human, Mouse, Rat
storage：Store at -20°C as received.