商品介绍

gene_symbol：HB EGF
Synonyms：DTR; DTS; DTSF; HEGFL
clone_name：OTI6F4
immunogen：Human recombinant protein fragment corresponding to amino acids 20-208 of human HBEGF (NP_001936) produced in E.coli.
predicted_size：22.9 kDa
background：Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor. [UniProtKB/Swiss-Prot Function]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG2b
host：Mouse
applications：WB
Recommend Dilution：WB 1:2000
reactivities：Human
storage：Store at -20°C as received.