商品介绍

gene_symbol：Cytokeratin 8
Synonyms：CARD2; CK-8; CK8; CYK8; K2C8; K8; KO
clone_name：OTI2F5
immunogen：Human recombinant protein fragment corresponding to amino acids 91-381 of human KRT8(NP_002264) produced in E.coli.
predicted_size：53.5 kDa
background：This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG2b
host：Mouse
applications：IHC, WB
Recommend Dilution：IHC 1:2000
reactivities：Human, Mouse, Rat
storage：Store at -20°C as received.