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gene_symbol:PCNA
Synonyms:ATLD2
clone_name:OTI2G7
immunogen:Full length human recombinant protein of human PCNA (NP_002583) produced in E.coli.
predicted_size:28.6 kDa
background:The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2b
host:Mouse
applications:IF, WB
Recommend Dilution:WB 1:2000, IF 1:50
reactivities:Human, Mouse, Rat, Monkey, Dog
storage:Store at -20°C as received.
gene_symbol:PCNA
Synonyms:ATLD2
clone_name:OTI2G7
immunogen:Full length human recombinant protein of human PCNA (NP_002583) produced in E.coli.
predicted_size:28.6 kDa
background:The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG2b
host:Mouse
applications:IF, WB
Recommend Dilution:WB 1:2000, IF 1:50
reactivities:Human, Mouse, Rat, Monkey, Dog
storage:Store at -20°C as received.