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gene_symbol:Oct4
Synonyms:Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4
clone_name:OTI7H1
immunogen:Full length human recombinant protein of human POU5F1(NP_002692) produced in HEK293T cell.
predicted_size:38.4 kDa
background:This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Mar 2010]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:IF, WB
Recommend Dilution:WB 1:200~1000, IF: 1:100
reactivities:Human, Rat, Mouse
storage:Store at -20°C as received.
gene_symbol:Oct4
Synonyms:Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4
clone_name:OTI7H1
immunogen:Full length human recombinant protein of human POU5F1(NP_002692) produced in HEK293T cell.
predicted_size:38.4 kDa
background:This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Mar 2010]
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:IF, WB
Recommend Dilution:WB 1:200~1000, IF: 1:100
reactivities:Human, Rat, Mouse
storage:Store at -20°C as received.