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gene_symbol:STAT4
Synonyms:SLEB11
clone_name:OTI2F3
immunogen:Full length human recombinant protein of human STAT4(NP_003142) produced in HEK293T cell.
predicted_size:85.8 kDa
background:The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:FC, IF, IHC, WB
Recommend Dilution:WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.
gene_symbol:STAT4
Synonyms:SLEB11
clone_name:OTI2F3
immunogen:Full length human recombinant protein of human STAT4(NP_003142) produced in HEK293T cell.
predicted_size:85.8 kDa
background:The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug
buffer:PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype:IgG1
host:Mouse
applications:FC, IF, IHC, WB
Recommend Dilution:WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
reactivities:Human, Mouse, Rat
storage:Store at -20°C as received.