商品介绍

gene_symbol：CRSP8
Synonyms：CRAP34; CRSP8; CRSP34; MED3; NEDSCAC; TRAP37
clone_name：OTI2A4
immunogen：Human recombinant protein fragment corresponding to amino acids 24-247 of human MED27(NP_004260) produced in E.coli.
predicted_size：35.3 kDa
background：The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
isotype：IgG1
host：Mouse
applications：WB
Recommend Dilution：WB 1:500~2000
reactivities：Human, Mouse, Rat
storage：Store at -20°C as received.