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Ku80 mouse mAb
  • 商城价格 登录后可查看价格
  • 货号 YP-Ab-00102
  • 品牌 优品生物 ( 经销商 )
  • CAS号 见包装
  • 规格/包装 53ul
  • 单位
  • 储存条件 -20°C/1 year
  • 现货状态 三个工作日

  • 数量

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developmental stage:Expression increases during promyelocyte differentiation.,disease:Individuals with systemic lupus erythematosus (SLE) and related disorders produce extremely large amounts of autoantibodies to p70 and p86.,domain:The EEXXXDDL motif is required for the interaction with catalytic subunit PRKDC and its recruitment to sites of DNA damage.,function:Single stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by p70. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The Ku p70/p86 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of t
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