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catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,cofactor:Binds 1 iron ion per subunit.,cofactor:Binds 1 manganese ion per subunit.,function:May play a role in the regulation of RNA biogenesis and/or mitosis. In vitro, dephosphorylates serine residues of skeletal muscle phosphorylase and histone H1.,similarity:Belongs to the PPP phosphatase family.,similarity:Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.,similarity:Contains 3 TPR repeats.,subcellular location:Predominantly nuclear. But also present in the cytoplasm.,subunit:Interacts with CDC16 and CDC27.,tissue specificity:Ubiquitous.,