catalytic activity:CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide.,disease:Defects in ST3GAL5 are the cause of Amish infantile epilepsy syndrome (AIES) [MIM:609056]. AIES is an autosomal recessive, infantile-onset symptomatic epilepsy associated with developmental stagnation and blindness.,function:Catalyzes the formation of ganglioside GM3 (alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D-glucosylceramide).,online information:GlycoGene database,online information:ST3Gal V,PTM:N-glycosylated.,similarity:Belongs to the glycosyltransferase 29 family.,tissue specificity:Ubiquitous. High expression in brain, skeletal muscle, placenta, and testis.,

非质量问题不退换