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PIWL4 rabbit pAb
  • 商城价格 登录后可查看价格
  • 货号 YP-Ab-12315
  • 品牌 优品生物 ( 经销商 )
  • CAS号 见包装
  • 规格/包装 53ul
  • 单位
  • 储存条件 -20°C/1 year
  • 现货状态 三个工作日

  • 数量

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function:Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Associates with secondary piRNAs antisense and PIWIL2/MILI is required for such association. The piRNA process acts upstream of known mediators of DNA methylation. Participates to a piRNA amplification loop. Besides their function in transposable elements repression, piRNAs are probably involved in other
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