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PMEL (ABT255) Mouse mAb
  • 商城价格 登录后可查看价格
  • 货号 YP-Ab-15696
  • 品牌 优品生物 ( 经销商 )
  • CAS号 见包装
  • 规格/包装 53ul
  • 单位
  • 储存条件 -20°C
  • 现货状态 三个工作日

  • 数量

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function:Could be a melanogenic enzyme. Could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.,similarity:Belongs to the Pmel-17/NMB family.,similarity:Contains 1 PKD domain.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subcellular location:Probably product of proteolytic cleavage.,tissue specificity:Preferentially expressed in melanomas. Some expression was found in dysplastic nevi. Not found in normal tissues nor in carcinomas.,
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