Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells . Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux . Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity . ; (Microbial infection) Acts as a receptor for hepatitis C virus in hepatocytes and appears to facilitate its cell entry . Binding between SCARB1 and the hepatitis C virus glycoprotein E2 is independent of the genotype of the viral isolate . ; (Microbial infection) Mediates uptake of M.fortuitum, E.coli and S.aureus. ; (Microbial infection) Facilitates the entry of human coron

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