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| 来源 | Isotype | 用途 | 交叉反应性 | 标记 | Ex/Em |
| Rat | IgG1, κ | FC | Human | PE | 565/578nm |
注：推荐用于流式细胞仪检测每次用量为2.5µl，对应2.5-5×105细胞或50µl外周血，实际使用时可以根据样品的实际情况适当调整抗体用量。
碧云天的BeyoFC™系列抗体，也称BeyoFC™流式抗体(Antibody for flow cytometry, FC antibody)，是经过充分验证适用于流式细胞仪(Flow Cytometry, FC)的高品质抗体，BeyoFC™系列流式抗体提供很多常见抗体，并提供多种荧光标记，便于选择合适的抗体和适当的荧光标记。
BeyoFC™系列流式抗体对于细胞的标记效果好，染色背景低，细胞分群更清晰。
BeyoFC™系列流式抗体特异性高，染色和细胞分群结果更为准确。
BeyoFC™系列流式抗体一致性好，批次间差异更小，结果重复性好。
抗体详细信息如下:
| About this Antibody | |
| Name | BeyoFC™ AC0805 Antibody |
| Category | Rat Monoclonal Antibody (mAb); Primary antibody; FC Antibody |
| Isotype | IgG1, κ |
| Clone number | BYMP4-25D2 |
| Purification method | Protein A affinity purification |
| About the Immunogen | |
| Gene ID | 3565 |
| Swiss Prot | P05112 |
| Synonyms | BSF1; IL-4; BCGF1; BSF-1; BCGF-1 |
| Background | The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. IL4 is considered an important cytokine for tissue repair, counterbalancing the effects of proinflammatory type 1 cytokines, however, it also promotes allergic airway inflammation. Moreover, IL-4, a type 2 cytokine, mediates and regulates a variety of human host responses such as allergic, anti-parasitic, wound healing, and acute inflammation. This cytokine has been reported to promote resolution of neutrophil-mediated acute lung injury. In an allergic response, IL-4 has an essential role in the production of allergen-specific immunoglobin (Ig) E. This pro-inflammatory cytokine has been observed to be increased in COVID-19 (Coronavirus disease 2019) patients, but is not necessarily associated with severe COVID-19 pathology. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2020] |
| 产品编号 | 产品名称 | 包装 |
| AC0805-125μl | BeyoFC™ PE anti-human IL-4 Antibody | 125μl |
| AFC060 | BeyoFC™流式检测细胞染色缓冲液 | 60ml |
| — | 说明书 | 1份 |
| 产品编号 | 产品名称 | 包装 |
| AC0805-500μl | BeyoFC™ PE anti-human IL-4 Antibody | 500μl |
| AFC250 | BeyoFC™流式检测细胞染色缓冲液 | 250ml |
| — | 说明书 | 1份 |
4ºC保存，一年有效。抗体须避光保存。BeyoFC™流式检测细胞染色缓冲液-20ºC可以保存更长时间。
注意事项：流式抗体通常不宜回收再使用。
相关步骤离心时，4ºC可更好的维持细胞完整性；同时根据细胞类型，可对离心力进行一定的优化。
如果需要同时进行细胞表面和细胞内抗原的流式检测，须先进行细胞表面抗原的染色，这样可以避免有些细胞表面抗原因为固定而无法被流式抗体所识别。
如需更多的BeyoFC™流式检测细胞染色缓冲液，可以另行单独采购BeyoFC™流式检测细胞染色缓冲液(C1711)。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
