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CD11c is the 150 kDa (Y-chain of the leucocyte integrin complex P1 50,95. The protein belongs to a family of related heterodimeric proteins designated CD11 in the classification system for human leucocyte differentiation antigens. The CD11 family shares a common 95 kDa li-chain (CD18). In addition to the p150,95 protein, this protein family contains two other members: leucocyte function associated-1 antigen (LFA-1, CD11a) and iC3b receptor (CD11b) (Hogg, 1997). CD11c is expressed strongly on monocytes and weakly on neutrophil granulocytes (Hogg, 1997). Natural killer cells and activated B and T cells also express CD11c (Luk, 1995). Anti-CD11c, KB90, was included in the Sixth International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with the CD11c antigen (Hogg, 1997).,官网链接:https://www.sigmaaldrich.cn/product/mm/fcmab179f
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