Myosin-VI has been found in the membrane ruffles at the leading edge of the Golgi complex. Myosin-VI moves along the actin in the opposite way of other known myosins to date, toward the minus end. It can exist as a dimer and a monomer and is thought to function as a non-processive motor with a 18nm working stroke. Myosin-VI has also been found in the brain, specifically the synapses. Myosin-VI deficiency (Snell’s waltzer disease) in the hippocampus causes a smaller number of synapses, short dendritic spines and astrogliosis. Myosin-VI may also be important in clathrin-mediated endocytosis of acid-type glutamate receptors. Recent research has implicated myosin-VI in the enrichment of proteins on the surface of axons.，官网链接：https://www.sigmaaldrich.cn/product/mm/abt42 默克 科研、开发、生产。 作为生命科学行业的全球领先供应商，我们致力于为科研、生物技术开发和生产，以及制药药物疗法开发和生产提供各类解决方案和服务。

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