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HOG is a clonal cell line derived from a surgically removed human oligodendroglioma (HOG) . HOG cells express oligodendrocyte markers including low levels of the 15-kDa form of myelin basic protein (MBP) and high levels of CNPase protein. HOG cells do not express GFAP, a astrocyte marker and were found to have minimal levels of glutamine synthetase activity . HOG cells express neurotransmitter receptors such as A2-adenosine, prostaglandin E1 (PGE1) and beta2-adrenergic receptores (beta-ARs) that activate the adenylate cylase signaling pathway . HOG cells also express muscarinic and histamine receptors that are linked to inositol phosphate signaling pathways .,官网链接:https://www.sigmaaldrich.cn/product/mm/scc163
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