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The UFH-001 triple negative CAIX+ human breast cancer cell line constitutively expresses CAIX under both hypoxic and normoxic conditions, exhibits an aggressive TNBC phenotype in vivo, and supports tumor growth in a mouse xenograft model . The constitutive expression of CAIX in UFH-001 cells facilitates its evaluation as a potential therapeutic target both in vitro and in vivo.
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UFH-001 cells are derived from MCF-10A cells, a spontaneously immortalized breast cancer epithelial cell line originating from breast tissue of a healthy female patient . UFH-001 cells were sorted for CAIX expression by flow cytometry .,官网链接:https://www.sigmaaldrich.cn/product/mm/scc210
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