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The BioTracker™ exosome membrane labeling probe series can be used for staining of the membranes of purified exosomes, which in turn permits imaging of labeled exosomes taken up by cells.SCT265 does not cause aggregation and has little effect on the properties of exosomes, permitting accurate observation of exosome dynamics.BioTracker™ exosome membrane labeling probes overcome issues with existing labeling dyes, including:1) self-particle formation2) an increase in size of the exosomes after labelingThree different fluorescence colors---green (SCT265), red (SCT266), and far red (SCT267)--- enable application in multiplexing experiments, such as observation of exosome localization in organelles.Add 10 uL DMSO to tube of green, red, or far red exosome membrane dye to create stock solution. SPECTRAL PROPERTIES:Ex 488nm/Em 490-540nmReferences:Kawata R, Oda S, Koya Y, Kajiyama H, Yokoi T. 2020. Macrophage-derived extracellular vesicles regulate concanavalin A-induced hepatitis by suppressing macrophage cytokine production. Toxicology. 443:152544.,官网链接:https://www.sigmaaldrich.cn/product/mm/sct265
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