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A cell-permeable, non-macrolide small molecule V-ATPase inhibitor that specifically targets the a3-b2 subunit protein protein interation of V-ATPase (IC₅₀ of 2.3 µM), in vitro. It is also shown to inhibit osteoclast resorption (IC₅₀ of 1.2 µM) on both synthetic hydroxyapatite surfaces and dentin slices in an in vitro osteoclast model, RANKL-differentiated RAW 264.7 cells, without significantly affecting RAW 264.7 cell viability or RANKL-mediated osteoclast differentiation.，官网链接：https://www.sigmaaldrich.cn/product/mm/672999
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